Fig. 9From: Effective investigation of murine femoral bone development utilizing correlative light and electron microscopy (CLEM)Schematic diagram of the sequence of murine femoral bone development at an early stage. The bone matrix at an early stage has low mineralization levels and is highly porous. As mineralization progresses, the areas around the osteocyte lacunae are filled with collagen fibrils, and mineralization occurs from the outer rim toward the inner lacunaBack to article page