Fig. 4From: Liquid chromatography-tandem mass spectrometry for pharmacokinetics evaluation of AZD5305, a selective PARP1 inhibitor, in micePlasma concentration–time curves of AZD5305 after a a single IV bolus injection in fasted ICR mice (●: 0.1 mg/kg, ■: 0.3 mg/kg, ▲: 1 mg/kg) and b a single oral administration in fasted ICR mice (●: 0.1 mg/kg, ■: 0.3 mg/kg, ▲: 1 mg/kg, ▼: 3 mg/kg) (mean ± SD, n = 5)Back to article page