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Journal of Analytical Science and Technology

Table 2 Antibacterial activities of KL18 and KL-PxxP against Gram-positive and Gram-negative bacteria

From: Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of action

Peptides

Antimicrobial activity (MIC: μM)a

B. subtilis

S. aureus

S. epidermidis

E. coli

S. typhimurium

P. aeruginosa

KL18

16

16

> 64

32

32

> 64

KL-PxxP

4

4

4

4

2

4

  1. aMIC (minimum inhibitory concentration) was determined as the lowest concentration of peptide that inhibits visible growth of bacteria
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