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Journal of Analytical Science and Technology

Table 1 Amino acid sequences and cytotoxic activities of the peptides used in this study

From: Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of action

Peptides

Amino acid sequences

Rta (min)

Net charge

HMb (µH)

Helicity (%)

KL18

KWLKKLLKLLKKLLKKLK

30.80

+ 9

0.876

58

KL-PxxP

KWLKKLLKPLKPLLKKLK

21.68

+ 8

0.794

31

  1. aRetention time (Rt) was measured using a C18 reversed-phase analytical HPLC column
  2. bHydrophobic moment (HM) was calculated online (http://heliquest.ipmc.cnrs.fr/cgi-bin/ComputParams.py)
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