Fig. 4From: Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of actionMembrane permeabilization caused by the peptides. A Peptide-induced membrane depolarization of S. aureus. Complete depolarization was induced by adding gramicidin D. B Membrane disruption induced by peptides. Peptide-induced membrane disruption is defined as the percent calcein leakage from PC/PG (1:1). after 10 min incubation with peptidesBack to article page