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Table 5 Determination of RIB in its pharmaceutical formulations by the proposed method and statistical comparison with a reported HPLC method

From: Nano-fluorescent quantum dots as substrates for determination of ribavirin in pharmaceuticals and human plasma as well as monitoring of its kinetic interaction with salmon sperm DNA

Pharmaceutical formulation

Equivalent concentration of analytes (µg/mL)

% Recoverya by the developed method ± SD

Claimed amount (mg)

% Recoverya by the reported methods ± SD

t-testb

F-testb

Ribavirin® capsules (200.00 mg)

4.00

102.81 ± 0.64

205.62

103.69 ± 1.09

1.70

2.87

  1. aThe values are the mean of five determinations
  2. bThe tabulated values of t-test and F test at 0.05% are 2.306 and 5.05, respectively