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Table 1 Linearity parameters of RIB by the proposed method as authentic and in spiked human plasma samples

From: Nano-fluorescent quantum dots as substrates for determination of ribavirin in pharmaceuticals and human plasma as well as monitoring of its kinetic interaction with salmon sperm DNA

Parameters

Authentic samples

Spiked plasma

Linearity range (µg/mL)

0.06–10.00

≈ 2.46 × 10–7 M–4.09 × 10–5 M

0.06–10.00

≈ 2.46 × 10–7 M–4.09 × 10–5 M

Correlation coefficient (r)

0.9998

0.9830

Determination coefficient (R2)

0.9997

0.9663

Slope (b)

0.0527

0.0577

SD of slope

0.00556

0.00353

Intercept (a)

1.18

1.17

SD of intercept

0.00023

0.000295

LOD (µg/mL)

0.014

0.016

LOQ (µg/mL)

0.04

0.05