From: A selective and sensitive LC-MS/MS method for the simultaneous determination of twopotential genotoxic impurities in celecoxib
Parameter
SHH
MAP
Solution stability
Theoretical concentration (ppm)
0.06
Percent recovery (n = 3)
At 0 h
98.2 ± 0.94
96.2 ± 1.24
At 12 h
101.4 ± 1.13
95.6 ± 0.91
At 24 h
102.6 ± 0.82
96.4 ± 0.88
At 48 h
99.8 ± 1.45
100.4 ± 1.36